自我审查:科学期刊应该拒绝发表自我实验吗?
Jonathan Pugh1, Dominic Wilkinson2,3,4,5,6, Julian Savulescu2,3
1Uehiro Oxford Institute, University of Oxford, Oxford, UK jonathan.pugh@uehiro.ox.ac.uk.
Journal of medical ethics
|September 10, 2025
概括
在癌症治疗中进行自我实验,就像病毒学家用型病毒疗法治疗自己的乳腺癌一样,需要进行道德评估. 出版此类研究需要指导,重点关注自主性,风险和伤害预防.
科学领域:
- 医学伦理 医学伦理
- 在瘤学瘤学.
- 病毒学 病毒学
背景情况:
- 医学上的自我实验正受到越来越多的关注,特别是在一个病毒学家用结性病毒疗法治疗自己的乳腺癌的情况下.
- 这一趋势需要为研究机构和期刊提供关于自我实验研究的出版的伦理准则.
研究的目的:
- 概述医学研究中自我实验的伦理维度.
- 为考虑发表涉及自我实验的研究的期刊制定道德指导.
- 为评估自我实验的伦理影响提供一个框架.
主要方法:
- 对最近关于乳腺癌瘤性病毒疗法自我实验的病例报告的分析.
- 审查研究伦理的基本原则:尊重自主权,合理的风险和预防伤害.
- 将伦理原则应用于案例报告,以评估出版的合理性.
主要成果:
- 自我实验本质上并非不道德,但需要严格的伦理评估.
- 基础研究伦理学原则可以指导自我实验中的伦理问题.
- 根据伦理原则,公布特定案例报告被认为是道德上合理的.
结论:
- 倡导由道德审查委员会和期刊编辑对自我实验研究进行个案评估.
- 关于决策算法的建议,以协助评估和指导这些研究的出版决策.
- 强调在医学自我实验中平衡创新与道德责任.
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