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Updated: Jan 18, 2026

Network Pharmacology Prediction and Metabolomics Validation of the Mechanism of Fructus Phyllanthi against Hyperlipidemia
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在大鼠中使用经过验证的UFLC-MS/MS方法对赛可萨宁A的药理动力学和口服生物利用性进行表征

Zhongwen Sun1, Chao Qiu1, Yiqiang An2

  • 1College of Medicine, Lishui University, Lishui, China.

Biomedical chromatography : BMC
|September 10, 2025
PubMed
概括

赛可沙尼A (SSa) 由于吸收有限和广泛的新陈代谢,口服生物利用性较差. 这项研究开发了一种LC-MS/MS方法,用于量化大鼠血中的SSa,揭示其药理动力学特征并告知治疗用途.

关键词:
在 LCMS/MS 中使用.生物可用性 生物可用性血液溶解 (hemolysis) 是一种药物动力学 药物动力学赛科沙宁A是一种

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