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肝周移植高血糖症:机制,相关因素,后果和管理 - - 系统性审查
Yekta Rameshi1, Simin Dashti-Khavidaki1,2, Soghra Rabizadeh3
1Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Endocrinology, diabetes & metabolism
|September 11, 2025
概括
肝移植期间的高血糖是肝移植后的常见问题,可能会导致并发症. 本综述综合了因素,后果和管理策略,以改善患者的治疗结果.
科学领域:
- 移植医学 移植医学
- 内分泌学 在内分泌学.
- 肝病学 肝病学是一种肝病学.
背景情况:
- 肝移植经常涉及代谢并发症,特别是移植期间的高血糖症.
- 这种情况带来了移植后并发症的风险,影响了移植和接受者的预后.
- 现有的研究提供了洞察力,但缺乏全面的管理协议.
研究的目的:
- 审查肝移植后高血糖症的机制,促成因素和后果.
- 提出基于证据的建议,用于管理移植期间高血糖症.
主要方法:
- 在PubMed,Scopus和UpToDate数据库中进行系统的文献搜索.
- 包括美国糖尿病协会指导方针.
- 在2025年2月之前,搜索没有时间限制.
主要成果:
- 高血糖的原因包括肝细胞损伤,胰岛素抵抗,手术压力和免疫抑制剂.
- 相关因素包括接受者,手术内和捐赠者的变量.
- 低血糖控制与感染增加,移植排斥,急性损伤,更长的住院时间和更高的死亡率相关.
结论:
- 考虑患者病史和临床状况的结构化方法对于有效的管理至关重要.
- 拟议的框架有助于医疗保健提供者管理肝周移植高血糖症.
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