脑卒中后抑郁症的趋势和差异 在缺血性脑卒中1年内
Maria X Sanmartin1,2, Jeffrey M Katz1,2, Mir M Ali3
1Departments of Radiology, Neurology, and Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY.
The Journal of neuropsychiatry and clinical neurosciences
|September 11, 2025
概括
脑卒中后抑郁症 (PSD) 不成比例地影响女性和非西班牙裔白人. 这项研究突出了PSD诊断的差异,强调了在代表性不足的群体中进行有针对性的查的必要性.
科学领域:
- 神经学 神经学
- 精神病学是一个精神病学.
- 公共卫生 公共卫生
背景情况:
- 脑卒中后抑郁症 (PSD) 是中风后的一种常见的神经精神疾病并发症.
- 现有的研究尚未完全阐明PSD诊断中的潜在差异.
- 了解这些差异对于公平的患者护理至关重要.
研究的目的:
- 为了调查中风后抑郁症 (PSD) 诊断的10年趋势.
- 检查与PSD相关的社会经济和临床因素.
- 确定急性缺血性中风 (AIS) 患者在PSD诊断中的潜在差异.
主要方法:
- 从2014年到2023年对AIS患者进行回顾性队列研究.
- PSD定义为新的重大抑郁症诊断或在中风后1年内开始服用抗抑郁药物.
- 统计分析包括趋势,双变量和多变量后勤回归.
主要成果:
- 在23,514名AIS患者中,15.0%患有PSD.
- 与男性和非白人患者相比,女性和非西班牙裔白人患者的PSD诊断率较高.
- 与增加PSD几率相关的因素包括女性性别,中年,中度中风严重程度 (NIHSS 6-15),和功能性结果差 (mRS 2-5).
结论:
- 女性,非西班牙裔白人患者,中年人和中度至重度中风或功能不良的人更有可能接受PSD诊断.
- 在中风幸存者中,对长期抑郁症查有极大需要.
- 需要特别注意种族少数民族人口,他们可能被诊断不足或治疗不足PSD.
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