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Updated: Jan 18, 2026

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用siRNA纳米复合体调节产卵前的胎盘功能

Xue Peng1,2, Xi Tan1,2, Li Dai1,2

  • 1Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu (X.P., X.T., L.D., W.X.).

Hypertension (Dallas, Tex. : 1979)
|September 11, 2025
PubMed
概括

这项研究揭示了线粒体DNA拷贝数和子宫前之间的联系. 它还引入了通过DMD@DPF纳米颗粒传递的siRNA SENP3,作为早期发作的先兆子的潜在治疗方法.

关键词:
这些都是DNA,线粒体DNA.门德尔的随机化分析.胎盘 胎盘 胎盘 胎盘孕产妇产前炎症 (pre-eclampsia) 是一个严重的疾病.怀孕 怀孕 怀孕 怀孕 怀孕

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Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
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