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Updated: Jan 18, 2026

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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Published on: June 23, 2019

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农业化学中的皮拉胺基架:从分子设计到应用

XinYi Zhang1, Wei Sun1, QiQi Yi1

  • 1State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Huaxi District, Guiyang 550025, China.

Journal of agricultural and food chemistry
|September 11, 2025
PubMed
概括

皮拉胺化合物由于其多样化的生物活性,在农药研究中至关重要. 本综述总结了它们的杀虫剂,杀菌剂,杀真菌剂和除草剂特性,有助于新农药的开发.

关键词:
生物活动是生物活动.皮拉胺胺的使用方法结构 - 活动关系.

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Direct alkylation of ammonia produces polyalkylated amines, along with a quaternary ammonium salt. To exclusively prepare primary amines, the azide synthesis method can be used.
Azide ions act as good nucleophiles and react with unhindered alkyl halides to form alkyl azides. Alkyl azides do not participate in further nucleophilic substitution reactions, thereby eliminating the chances of polyalkylated products. Alkyl azides are reduced by hydride-based reducing agents, like lithium aluminum...
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Amides are synthesized by treating carboxylic acids with amines in the presence of dehydrating agents like dicyclohexylcarbodiimide (DCC).
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