巴伊卡林:在食品和功能应用中将传统医学和现代科学联系起来
Chen-Qin Xu1, Yi-Lang Zhong1, Tao Liu2
1Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China.
Naunyn-Schmiedeberg's archives of pharmacology
|September 11, 2025
概括
贝卡林是来自Scutellaria baicalensis的天然化合物,具有强大的抗炎和抗氧化作用. 它在功能性食品和药物中具有潜在的应用,新的研究重点是传递系统,以提高其有效性.
科学领域:
- 药理学和食品科学 药理学和食品科学
- 自然产品化学 自然产品化学
- 传统中国医药 传统中国医药
背景情况:
- 巴伊卡林是一种来自Scutellaria baicalensis的黄类化合物,与药物-食品同质性 (MFH) 理论保持一致.
- 它在治疗和功能性食品中具有多样化的生物活动和应用.
研究的目的:
- 审查最近 (2018-2024) 在贝卡林的生物活动和药理机制的进展.
- 探索贝卡林在食品科学中的新兴应用及其治疗潜力.
主要方法:
- 文献综述综合了最近关于baicalin的研究.
- 对贝卡林分子点和途径 (例如NF-κB,Nrf2) 的分析.
- 研究配方策略 (例如,纳米封装,β-环氧化复合物) 以提高溶解性和稳定性.
主要成果:
- 巴伊卡林具有显著的抗炎,抗氧化,抗瘤,抗病毒和抗菌性质.
- 它调节关键信号通路,并显示在水产养殖料和营养药物输送方面具有前途.
- 创新的配方提高了百卡林的溶解度七倍,克服了稳定性和溶解度的挑战.
结论:
- 贝卡林证明了治疗的多功能性,在心血管,代谢和神经疾病中具有临床疗效.
- 纳米输送系统可以提高贝卡林的生物可用性,从而改善治疗结果.
- 巴伊卡林是功能性食品开发和预防性医疗保健的有希望的候选者,与天然产品趋势保持一致.
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