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Updated: Jan 6, 2026

Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51
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Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51

Published on: February 13, 2019

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在从线粒到介质重组过渡期间,Rad54-和Hed1-介导的Rad51调节的结构基础

Yeonoh Shin1, Michael T Petassi1, Aidan M Jessop1

  • 1Department of Biochemistry & Molecular Biophysics, Columbia University Irving Medical Center, New York, NY 10032.

Proceedings of the National Academy of Sciences of the United States of America
|September 11, 2025
PubMed
概括

研究人员发现了Rad54和Hed1蛋白如何调节DNA修复蛋白Rad51. 结构显示,Rad54促进了线粒重组,而Hed1在半分裂过程中抑制了Rad51进行同源重组.

关键词:
头部1 头部1 头部1在Rad51中,使用了Rad51.拉德54 Rad54 在线播放同类的重组组合.介质变化 (meiosis) 是一种变质的过程.

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