随着皮肤前庭隔膜缺陷关闭后,心房失常率的双相增加
Brendan J Burke1, Ghazaleh Goldar2,3, Jeevanantham Rajeswaran4
1Children's Institute, Division of Cardiology and Cardiovascular Medicine, Department of Heart, Vascular and Thoracic, Cleveland Clinic Children's, Cleveland, Ohio.
Journal of the Society for Cardiovascular Angiography & Interventions
|September 11, 2025
概括
经过皮肤穿透性心房隔膜缺陷 (ASD) 关闭的老年人面临着心房失常症 (AA) 的双相风险. 对于60岁及以上的患者,建议进行例行节律监测.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 成年人的先天性心脏病
背景情况:
- 关于成年人皮穿性心房隔膜缺陷 (ASD) 关闭时的年龄和随后的心房失常 (AA) 负担,存在相互矛盾的数据.
- 影响AA后ASD关闭的患者特异性因素需要进一步调查.
研究的目的:
- 为了确定ASD关闭时的年龄对AA后手术负担的影响.
- 通过皮肤关闭ASD后,确定与AA发展相关的患者特异性因素.
主要方法:
- 在2010年1月至2022年7月期间,对197名接受皮肤透性ASD关闭的患者进行了分析.
- 使用非线性逻辑时间分解混合效应模型来分析纵向AA数据.
- 包括患者人口统计,心声回声参数和节律监测记录.
主要成果:
- 关闭后的AA表现出一个双相模式:早期达到峰值和晚期上升至6年.
- 60岁或以上的年龄与较高的早期和晚期AA患病率有关.
- 年龄较大,E/A比较低,射出率较低,三腹吐,RV功能障碍和RV扩张与AA可能性增加有关.
结论:
- 老年患者经历了皮肤穿透ASD关闭后AA的持续双相风险.
- 常规节律监测对于60岁及以上的ASD关闭后患者至关重要.
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