相关实验视频
Updated: Jan 18, 2026

11:46
Shotgun Lipidomics of Rodent Tissues
Published on: November 18, 2022
2.6K
超慢性脂质性肺炎的悖论 超慢性脂质性肺炎的矛盾
1Division of Thoracic Oncology Shizuoka Cancer Center Shizuoka Japan.
Respirology case reports
|September 11, 2025
概括
本案例研究详细介绍了一个患有非小细胞肺癌的单个患者的复发性外源性脂质性肺炎. 它强调了识别导致肺炎的特定暴露的重要性.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 放射学 放射学是指放射学
背景情况:
- 外源性脂质性肺炎 (ELP) 是一种罕见的肺部疾病,由吸收或吸入含脂质物质引起.
- 接受化疗的非小细胞肺癌 (NSCLC) 患者可能出现新的肺透,需要差异诊断.
研究的目的:
- 报告第一例异源性脂质性肺炎复发病例,该病例发生在单个患者身上,该病例是由多种不同的异源物质引起的.
- 强调特征性放射学发现和详细的患者暴露史在癌症治疗期间管理肺部并发症的诊断实用性.
主要方法:
- 一个70岁的女性患有EGFR突变NSCLC的病例报告.
- 连续的胸部CT扫描来评估肺部透.
- 支气管镜检查与支气管膜洗,以确定含脂的巨细胞.
- 详细的历史记录,以确定潜在的外部暴露.
主要成果:
- 该患者经历了三次ELP,每次都与不同的外源暴露有关:鼻内油,煤油加热器使用和鼻内保湿油.
- 胸部CT始终显示地面玻璃的不透明度与疯狂的铺路模式,主要在右中叶.
- 支气管镜检查证实了带有脂质的,CD163阳性的泡性巨细胞.
- 所有事件都在识别出违规行为者停止使用后得到解决.
结论:
- 复发性ELP可以由单个患者的多种无关异源物质触发.
- 放射学模式和彻底的暴露史对于诊断ELP至关重要,特别是在新肺透的癌症患者中.
- 临床医生应考虑ELP作为在癌症治疗期间新肺部发现的差异诊断.
相关概念视频
Pneumonia II: Pathophysiology
2.6K
The pathophysiology of pneumonia involves the following steps:
2.6K
Formation of Lipopolysaccharides
556
Lipopolysaccharides (LPS) are crucial components of the outer membrane of Gram-negative bacteria, serving both structural and functional roles. It contributes to membrane stability and protects bacteria from host immune responses. LPS is composed of three major regions—lipid A, a core oligosaccharide, and an O antigen. The biosynthesis and assembly of LPS involve a highly coordinated set of enzymatic reactions and transport mechanisms. Additionally, LPS is recognized as an endotoxin,...
556
Asymmetric Lipid Bilayer
9.6K
Biological membranes show uneven distribution of different types of lipids in the inner and outer layers, resulting in transverse asymmetric membranes. The treatment of the erythrocyte membrane with the enzyme phospholipase confirmed the asymmetric nature of the lipid bilayer. The enzyme hydrolyzes lipids into fatty acids and hydrophilic groups. The phospholipase acts only on the outer layer of the membrane, while the inner layer remains intact. The phospholipase treatment resulted in 80%...
9.6K
Biosynthesis of Lipids
537
Microbial membranes exhibit remarkable diversity in lipid composition, reflecting evolutionary adaptations to various environmental conditions. The three domains of life—Bacteria, Archaea, and Eukarya—synthesize membrane lipids through distinct biosynthetic pathways, leading to fundamental structural differences that impact membrane stability, function, and adaptability.Fatty Acid-Based Lipids in Bacteria and EukaryaBacteria and eukaryotes share a common fatty acid biosynthesis...
537
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
4.2K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
4.2K
Overview of Lipid Metabolism
4.9K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
4.9K

