饮食摄入量与纽芬兰人口糖尿病前期患病率之间的关联:一个横截面研究
Shanshan Yu1, Hongwei Zhang2, Jianling Du1
1Department of Endocrinology, First Affiliated Hospital of Dalian Medical University, Dalian, China.
Frontiers in nutrition
|September 11, 2025
概括
调整为体重的较高摄入量显著降低了高风险人群中糖尿病前期风险. 这凸显了体重正常化对指南和代谢健康的重要性.
科学领域:
- 营养生物化学 营养生物化学
- 代谢健康 代谢健康
- 人口健康 人口健康
背景情况:
- 新兴研究通过抗氧化和抗炎途径将 (Se) 与葡萄糖代谢联系起来.
- 关于在血糖调节中的作用的特定人群数据有限.
- 纽芬兰的人口,具有遗传同质性和高肥胖率,为这项调查提供了一个独特的背景.
研究的目的:
- 调查饮食摄入量与糖尿病前期患病率之间的关联.
- 在纽芬兰的特定人口群体中探索这种联系.
主要方法:
- 对来自CODING研究的2665名参与者的横截面研究.
- 糖尿病前期,根据美国糖尿病协会 (American Diabetes Association) 的标准定义,是指快食葡萄糖受损.
- 通过食物频率调查问卷评估的饮食摄入量 (绝对和体重调整).
- 统计分析包括多变量逻辑回归,通用添加模型和零碎回归.
主要成果:
- 体重调整后的摄入量与糖尿病前期患病率有显著的反向非线性关系.
- 观察到1.42μg/kg/d的值效应;摄入量低于这个水平,降低了69%的糖尿病前期风险.
- 绝对摄入量 (μg/d) 与糖尿病前期没有显著相关性.
结论:
- 根据体重调整的摄入量与这种高风险人群的糖尿病前期风险相反相关.
- 这些发现强调了体重正常化在评估的代谢作用中的关键作用.
- 这项研究为制定更准确的摄入指南提供了信息.
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