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Updated: Jan 18, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
11:45

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Published on: August 22, 2018

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通过催化循环化合成的阿扎斯皮罗[n.2]的酶选择性和二元选择性合成

Joshua K Sailer1, Duc Ly1, Andrew Wang1

  • 1Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States.

ACS catalysis
|September 11, 2025
PubMed
概括

这项研究提出了一种合成螺旋cyclopropanes的新方法,在药物发现中至关重要. 使用性迪催化剂,它实现了高度选择性的阿扎斯皮罗-[n.2]-的合成,提高了药物开发效率.

关键词:
不对称的催化剂.碳化合物的碳化合物催化剂-基质的识别循环制剂的使用迪罗是一种.螺旋化合物是螺旋化合物中的一种.

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