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Updated: Jan 18, 2026

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使用PVP-K30和HPMC E3固体分散剂通过溶剂蒸发方法制备和评估瓦尔萨坦口腔可分散片

Mahsa Zaghian1,2, Alireza Homayouni2, Zahra Keshavarz1

  • 1Pharmacy Students' Research Committee, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.

Research in pharmaceutical sciences
|September 11, 2025
PubMed
概括

这项研究使用固体分散 (SD) 技术改善了沙坦 (Val) 的口服生物可用性,使用口腔可分散片 (ODT) 中的聚乙烯 (PVP) 和基基甲基纤维素 (HPMC) 载体. 提高了可溶性和溶解率,使高血压患者受益.

关键词:
在HPMC中,HPMC是指HPMC.在PVP中,PVP是PVP.固体分散的分散方式瓦尔萨坦 瓦尔萨坦 瓦尔萨坦

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