相关实验视频
Updated: Jan 18, 2026

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Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
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孕期糖尿病的终身管理:一个叙事性回顾
Qing-Jing Luo1,2, Qiang Ni1,3
1West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
World journal of clinical cases
|September 11, 2025
概括
孕期糖尿病 (GDM) 对母亲和婴儿构成重大风险. 早期检测,改变生活方式和个性化护理对于管理GDM和预防长期代谢障碍至关重要.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 孕期糖尿病 (GDM) 是一个日益严重的全球健康问题,与母亲的年龄,肥胖和生活方式因素有关.
- 对于母亲和后代来说,GDM具有显著的短期和长期健康风险,突出其在代际代谢疾病预防中的作用.
研究的目的:
- 审查目前关于GDM病理生理学,诊断,管理,并发症和个性化治疗的证据.
- 综合关于GDM的信息,以改善临床理解和患者的治疗结果.
主要方法:
- 根据PRISMA指南进行了全面的叙事审查.
- 在主要数据库 (PubMed,Scopus,Web of Science,EMBASE) 的搜索中,确定了2017年至2025年期间发表的相关英语研究.
- 在选了512个记录后,根据质量,相关性和与审查目标的一致性选择了55项研究.
主要成果:
- GDM源于胰岛素抵抗,β细胞功能障碍,免疫问题和胎盘炎症,可能通过表观遗传学影响胎儿发育.
- 孕产妇的风险包括2型糖尿病,心血管疾病,子宫前和剖腹产的7-10倍增加.
- 后代面临巨症,新生儿低血糖症和未来代谢/心血管问题的风险. 生活方式干预,甲胺或胰岛素是关键的治疗方法,支持产后护理和咨询.
结论:
- GDM需要基于精度的生命周期管理策略.
- 未来的研究应该专注于早期检测,生物标志物验证,标准化诊断和文化适应的干预措施,以提高母亲和儿童健康结果.
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