患有COVID-19后急性后果的成年人睡眠质量和效率
Leidys Gutiérrez-Martínez1,2, William Cody Reynolds2, Isabel Abril2
1Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, United States.
Sleep advances : a journal of the Sleep Research Society
|September 11, 2025
概括
患有COVID-19 (PASC) 后急性后果的人报告睡眠质量不佳影响日常生活,尽管有足够的客观睡眠效率. 睡眠质量的恶化与抑郁症状相关,这表明睡眠是改善PASC患者结果的目标.
科学领域:
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
- 精神病学是一个精神病学.
背景情况:
- 睡眠障碍与负面的健康结果有关.
- 患有COVID-19 (PASC) 后急性后续症患者经常经历睡眠障碍.
- 这项研究调查了非住院PASC个体的睡眠质量和效率.
研究的目的:
- 检查PASC患者的睡眠质量和效率.
- 评估睡眠参数与神经精神症状 (焦虑,抑郁,PTSD) 和疲劳之间的关联.
- 确定改善PASC患者福祉的潜在可修改因素.
主要方法:
- 招募了61名非住院PASC参与者 (COVID-19感染≥2个月前).
- 使用匹兹堡睡眠质量指数 (PSQI) 测量睡眠质量.
- 使用Fitbit Charge-4评估了目标睡眠效率,并使用了针对神经精神病症状和疲劳的验证问卷. 使用了多变量线性回归.
主要成果:
- 没有发现PSQI得分与客观睡眠效率之间的关联.
- 近97%的参与者报告睡眠质量不佳,其中85%的人经历了日常活动的干扰.
- 较高的抑郁症得分与更差的睡眠质量相关;焦虑,PTSD和疲劳得分与整体睡眠质量没有直接相关,但与特定的PSQI组件有关. 目标睡眠效率与任何测量变量无关.
结论:
- 尽管客观的睡眠效率,但PASC患者表现出显著的主观睡眠困难,影响日常生活.
- 人们认为睡眠质量差,特别是与抑郁症状相关,这凸显了睡眠是干预的关键领域.
- 解决PASC患者的睡眠障碍可能会改善他们的整体生活质量.
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