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Updated: Jan 18, 2026

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function
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优化犬类T细胞的激活,扩张和转导.

Treyvon W Davis1, Jennifer C Holmes2, Arissa He3

  • 1Department of Biological Sciences, College of Veterinary Medicine, North Carolina State University, North Carolina, Raleigh, United States of America.

PloS one
|September 11, 2025
PubMed
概括

优化犬类T细胞免疫疗法需要有效的T细胞激活. 板结合抗体,特别是αCD3克隆CA17.6F9与αCD28克隆5B8或PMA/ionomycin,增强T细胞激活,扩张和转导,以获得更好的癌症治疗结果.

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