在患有川崎病的青春期前患者中心肺功能受损
Yen-Sen Lu1, I-Ching Huang2, Yen-Hsien Wu3
1Department of Physical Medicine and Rehabilitation, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Clinics (Sao Paulo, Brazil)
|September 11, 2025
概括
与健康同龄人,特别是男孩相比,患有川崎病 (KD) 史的儿童有氧能力和运动耐受性降低. 为了他们的心肺健康,建议定期进行体育活动.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 运动生理学 运动生理学
- 心肺健康 心肺健康
背景情况:
- 川崎病 (KD) 是一种影响冠状动脉的关键儿科疾病.
- 在青春期前的儿童中,KD对心肺功能的长期影响需要进一步研究.
- 评估运动能力对于了解KD幸存者的功能恢复和未来健康至关重要.
研究的目的:
- 调查和比较前青春期儿童的心肺功能与健康对照,有川崎病 (KD) 史.
- 为了确定KD幸存者在运动能力中的潜在的性别特异性差异.
- 为儿童KD患者提供基于证据的身体活动建议.
主要方法:
- 一项回顾性队列研究涉及117名青春期前KD患者和121名年龄,性别和BMI匹配的健康对照.
- 所有参与者都接受了心肺运动测试 (CPET) 和肺功能测试.
- 2014年1月至2023年12月期间,从台湾的两个医疗中心收集了数据.
主要成果:
- 在KD组和对照组之间没有发现肺功能或一般人口统计学方面的显著差异.
- 凯迪组的有氧能力显著降低 (24.32比26.08毫升/分钟/公斤) 和运动耐受度高峰 (35.43比38.48毫升/分钟/公斤) (p < 0.001).
- 这些差异在男性中更为明显,在女性中没有观察到统计学上显著的变化.
结论:
- 与健康的同龄人,特别是男性相比,有KD病史的青春期前儿童的有氧能力和运动耐受性降低了.
- 尽管运动能力有所降低,但KD幸存者可以安全地参加中度至强度的体力活动.
- 鼓励定期炼对于维持儿科KD患者的长期心肺健康至关重要.
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