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Updated: Jan 18, 2026

Reliably Engineering and Controlling Stable Optogenetic Gene Circuits in Mammalian Cells
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校准基因调节的参数化随机布尔网络模型,使用单个稳定状态基因表达特征

Mohammad Taheri-Ledari1, Sayed-Amir Marashi2, Mohammad Hossein Ghahremani3

  • 1Laboratory of Complex Biological Systems and Bioinformatics (CBB), Department of Bioinformatics, Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, 1417614411, Iran.

Mathematical biosciences
|September 11, 2025
PubMed
概括

本研究介绍了一种基于模拟的方法,使用单基因表达数据来估计随机布尔网络 (BNs) 的参数. 这种方法有助于理解基因调节网络 (GRNs) 和开发个性化医学策略.

关键词:
布尔网络是一个布尔网络.癌症细胞系的癌症细胞系基因监管网络是基因监管网络.在NSCLCLC中,我们可以看到.个性化 个性化个性化医疗是个性化的医疗.

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