在作物生长期间的污水污泥修改土壤中抗生素耐药性风险的动态演变:基于现场的元基因组学观点
Junqiao Zhao1, Zhenyu Guo1, Langjun Tang1
1Department of Pharmaceutical & Biological Engineering, School of Chemical Engineering, Sichuan University, Chengdu, 610065, China.
Environmental research
|September 11, 2025
概括
污水污泥在土壤中的应用会传播抗生素耐药性基因 (ARG). 一项实地研究发现AR风险波动,但大部分是可回收的,这表明针对可持续土地利用的有针对性的管理.
科学领域:
- 环境微生物学环境微生物学
- 污水处理 污水处理 污水处理
- 农业科学 农业科学
背景情况:
- 污水污泥是废水处理的全球副产品.
- 污泥的土地应用将抗生素耐药性基因 (ARG) 传播到生态系统中,对生态安全和公共健康构成风险.
- 在污泥土地应用期间评估抗生素耐药性 (AR) 风险至关重要.
研究的目的:
- 在作物生长期间监测污泥修改土壤中AR风险的动态演变.
- 评估污泥修改对土壤微生物群落,ARG,移动遗传元素 (MGE) 和毒性因子 (VF) 的影响.
- 提出一个时间敏感的控制策略,以在"一健康"模式下减轻AR风险.
主要方法:
- 实地研究涉及在污泥改性土壤中种植三种作物.
- 在整个作物生长周期中监测AR风险.
- 基因组测序来分析ARG,MGE,VF及其共同发生.
主要成果:
- 泥修改对土壤微生物群落和耐药物产生了持久但在很大程度上可以恢复的影响.
- AR风险的演变是非线性的和波动性的,主要是由土壤微生物社区重建驱动的.
- 分析了ARG,MGE和VF的同时发生模式.
结论:
- 为可持续的污泥土地应用提出了针对关键风险窗口的时间敏感控制策略.
- 该战略旨在在"一健康"框架内减轻AR风险.
- 可持续的污泥管理需要考虑作物特定因素和动态风险演变.
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