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Updated: Jan 18, 2026

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SHLP2通过抑制ETV5/GSDMD信号通路介导的热灭菌来缓解过敏性喘

Wenlong Zhang1, Yan Wang2, Chenhui Ma2

  • 1Department of Respiratory and Critical Care Medicine, Jiangnan University Medical Center, 68 Zhongshan Road, Wuxi 2140002, Jiangsu Province, PR China; Wuxi School of Medicine, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, Jiangsu Province, PR China.

Cellular signalling
|September 11, 2025
PubMed
概括

人类蛋白模仿-2 (SHLP2) 可能治疗过敏喘 (AA). 较低的SHLP2水平与AA相关,并且通过调节ETV5/GSDMD通路,SHLP2补充剂可以减少小鼠的肺炎和细胞损伤.

关键词:
过敏性喘是一种过敏性喘.电子交易系统的变体转录因子5 (ETV5)GSDMDMD的总体发展目标是什么人类蛋白质模仿-2 (SHLP2)热灭菌的发生.

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