儿童患者体质指数,尿液代谢障碍和结石病之间的关联
Jingyi Yang1, Jie Ni1, Yu Zhou1
1Department of Nephrology, Beijing Children's Hospital, National Center for Children's Health, Capital Medical University, No. 56 Nanlishi Street, Xi Cheng District, Beijing, 100045, China.
Pediatric nephrology (Berlin, Germany)
|September 11, 2025
概括
肥胖本身可能不会导致儿童患结石,但代谢问题和尿路形状的不同会增加风险. 促进流体摄入和更好的营养是儿科结石病的关键预防策略.
科学领域:
- 儿科脏病学 儿科脏病学
- 代谢障碍 代谢障碍 代谢障碍
- 尿病研究 尿病研究
背景情况:
- 儿童肥胖,代谢障碍和结石形成之间的关系尚未完全理解.
- 现有的研究对儿科患者群体中这些关联提出了相互矛盾的证据.
研究的目的:
- 调查身体质量指数 (BMI),尿路代谢障碍和儿科石病之间的关联.
- 综合当前关于儿童和青少年结石风险因素的证据.
主要方法:
- 在主要数据库 (PubMed,Embase,Web of Science,Cochrane Library,Scopus) 进行了系统的文献搜索,截至2023年6月30日.
- 包括的研究是病例控制,队列和横截面设计,涉及21岁或更年轻的石病患者.
- 通过AHRQ和NOS标准来评估研究质量,但异质性排除了元分析.
主要成果:
- 超性尿,低性尿和高性尿在儿科结石病中很常见.
- 肥胖儿童的尿矿物质概况因地区,饮食和遗传学而异.
- 建议饮用液体和改善营养,以减轻石头风险因素.
结论:
- 肥胖不是儿科结石的唯一预测因素;代谢因素和尿路特征的组合增加了倾向.
- 个人代谢评估和增加液体摄入量是有效的,低成本的预防策略.
- 像%BF和BRI这样的替代指标可以补充BMI来评估儿科营养状况.
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