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血清25-基维生素D度与美国学龄前儿童的呼吸道感染之间的关联:基于人口的研究

Yingli Lin¹, Li Tian², Qi Chen³

¹Department of Early Childhood Education, Shaoxing Vocational & Technical College, Shaoxing, Zhejiang, China.

European journal of pediatrics

|September 11, 2025

概括

维生素D缺乏会增加学龄前儿童呼吸道感染的风险. 有针对性的查和补充可以帮助减少弱势群体的疾病.

科学领域:

儿科健康儿科健康
营养免疫学营养免疫学
公共卫生公共卫生

背景情况:

维生素D缺乏与儿科呼吸系统问题有关,但学龄前儿童的证据不一致.
了解维生素D在幼儿呼吸系统健康中的作用,对于公共卫生倡议至关重要.

研究的目的:

调查血清25-基维生素D[25(OH) D]水平与美国学龄前儿童的呼吸道感染之间的关联.
鉴定由于维生素D缺乏而面临更高呼吸道感染风险的学龄前儿童的特定子组.

主要方法:

从2007-2016年NHANES队列中对3316名2-6岁儿童进行了横截面分析.
维生素D状态的分类 (缺乏,不足,充足) 和呼吸道结果的评估 (感冒,严重感染).
多变量逻辑回归调整为混因子,严格评估剂量反应和子组异质性.

主要成果:

维生素D缺乏 (8.1%的患病率) 与呼吸道感染的几率增加了56% (aOR: 1.56).
在头部/胸部感冒 (aOR: 1.47) 和特定子组中观察到更高的风险:4-6岁,女性,低收入家庭和体重不足的儿童.
接触二手烟增加了与缺乏相关的风险,而足够的维生素D摄入量显示了风险减轻的趋势.

结论:

维生素D缺乏是学龄前儿童呼吸道感染增加的独立危险因素.
支持有针对性的查和维生素D补充策略,以减少幼儿发病率,特别是在脆弱人群中.

关键词:

25 基维生素 D 的含量.尼汉斯 (NHANES) 是一个名人.幼儿园儿童学龄前儿童呼吸道感染呼吸道感染维生素D缺乏症是因为缺乏维生素D.

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