它仍然是一个秘密的疾病 - 随机对照试验中的临床图像对hidradenitis suppurativa进行随机对照试验
Pernille Lindsø Andersen1, Gregor Borut Jemec1,2, Sam Polesie3,4,5
1Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.
The Journal of dermatological treatment
|September 12, 2025
概括
尽管临床图像很重要,但它很少被用于Hidradenitis suppurativa (HS) 随机对照试验 (RCT). 更多的图像使用可以提高HS研究中的透明度和患者沟通.
科学领域:
- 皮肤病学 皮肤病学
- 医疗成像医学成像
- 临床研究 临床研究
背景情况:
- 补腺炎 (HS) 是一种慢性炎症性皮肤疾病,对生活质量有重大影响.
- 在历史上,HS的研究不足,但最近的随机对照试验 (RCT) 提供了新的治疗见解.
- 通过评分系统传播定量数据是标准的,但从临床图像获得的视觉数据的探索较少.
研究的目的:
- 评估HS随机对照试验 (RCT) 中临床图像传播的程度.
- 评估临床图像如何为HS研究的透明度和非专业人士沟通做出贡献.
主要方法:
- 对265个已识别的文章进行了系统审查.
- 37篇文章符合审查的纳入标准.
- 每项试验都分析了临床图像的存在和数量,以及描绘的患者.
主要成果:
- 在37项试验中的15项 (40.5%) 中,临床图像存在,在4,327名患者中,仅显示33名患者 (0.7%).
- 在2020年之前发表的文章中,包含照片的频率更高 (p=0.008).
- 在HSRCT中包含图像的比例略高于银病和亚托皮性皮炎研究中的比例.
结论:
- 鉴于皮肤病学的视觉性质,HSRCT中临床照片的有限使用值得注意.
- 增加临床图像的传播可以提高研究透明度,医疗教育和患者沟通.
- 标准化的照片协议和道德考虑对于实施更广泛的图像使用至关重要.
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