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Updated: Jan 18, 2026

A Computerized Test Battery to Study Pharmacodynamic Effects on the Central Nervous System of Cholinergic Drugs in Early Phase Drug Development
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使用长效注射抗精神病药物的患者的受体占用率变化和精神状态之间的相关性:MIDILIA试点研究

James R O'Neill1,2,3, Christopher Wilson2, Mark A Horowitz4,5

  • 1School of Medicine, University of Leeds, UK.

BJPsych open
|September 12, 2025
PubMed
概括

在抗精神病剂剂量周期期间,多巴胺D2受体占用率的更快降低可能会使积极的精神病症状恶化. 较慢的减少可能有助于最大限度地减少这些影响,这表明受体占用率变化和症状出现之间存在联系.

关键词:
精神错乱是一种精神病.这是一种抗精神病药物.长效的注射剂 长效的注射剂药物动力学 药物动力学心理药理学 心理药理学

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