来自Plectranthus amboinicus的生物金属转化:复杂物,纳米粒子和治疗应用
Eishah Mohammed Ali Mohsen1, Adel A M Saeed2, Abdul-Rahman Alawi Bin Yahia3
1Department of Chemistry, Faculty of Education, University of Aden, Aden, Yemen.
International journal of nanomedicine
|September 12, 2025
概括
使用植物提取物的绿色合成创造了具有强大的抗微生物,抗氧化剂和抗癌性能的金属复合物和纳米粒子. 铜复合物在抗菌活性方面表现出色,而氧化铜纳米颗粒显示出优异的抗氧化和抗癌作用,证明了治疗潜力.
科学领域:
- 材料科学 材料科学 材料科学
- 纳米技术纳米技术
- 生物技术是生物技术.
背景情况:
- 金属复合物和纳米颗粒的绿色合成由于其抗微生物,抗氧化剂和抗癌特性而具有治疗潜力.
- 纳米材料的有效性取决于受控的制剂影响细胞透和破坏的尺寸和形状.
- 植物提取物为绿色合成提供了具有成本效益和效率的途径,尽管优化至关重要.
研究的目的:
- 为了合成铜,和复合物及其相应的金属氧化物纳米颗粒,使用Plectranthus amboinicus*的黄.
- 描述合成的材料并评估它们的抗微生物,抗氧化剂和抗癌活性.
- 为了研究癌细胞中诱导亡的机制.
主要方法:
- 通过将金属与Plectranthus amboinicus* flavonoids反应而合成的金属复合物;来自甲醇提取物的纳米颗粒.
- 使用UV-Vis,FT-IR,XRD,1H NMR和FESEM进行表征.
- 通过抗微生物试验 (细菌,真菌),抗氧化剂试验 (DPPH,ABTS) 和抗癌试验 (AML,Calu-3细胞) 来评估生物活性,并通过流细胞计测试来评估亡.
主要成果:
- 纳米金属复合体和氧化物纳米粒子的成功合成,通过表征技术证实了这一点.
- 铜复合体对测试的细菌和真菌表现出优异的抗菌活性.
- 氧化铜纳米颗粒表现出强大的抗氧化和抗癌作用,诱导癌症细胞系中的亡.
结论:
- 使用*Plectranthus amboinicus*进行绿色合成,可以产生有效的纳米金属复合物和纳米粒子,用于治疗.
- 合成的材料显示出显著的抗微生物,抗氧化剂和抗癌活性,包括亡诱导.
- 需要进一步的研究来优化这些绿色合成方法的临床应用.
更多相关视频
13:34Generation of Scalable, Metallic High-Aspect Ratio Nanocomposites in a Biological Liquid Medium
Published on: July 8, 2015
9.5K
10:31Detection and Recovery of Palladium, Gold and Cobalt Metals from the Urban Mine Using Novel Sensors/Adsorbents Designated with Nanoscale Wagon-wheel-shaped Pores
Published on: December 6, 2015
28.6K
相关概念视频
00:56Extraction: Advanced Methods
1.1K
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
1.1K
02:51Metal-Ligand Bonds
24.0K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
24.0K
00:57The Periodic Table and Organismal Elements
200.1K
Overview
200.1K