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Updated: Jan 18, 2026

Targeting Alpha Synuclein Aggregates in Cutaneous Peripheral Nerve Fibers by Free-floating Immunofluorescence Assay
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Published on: June 25, 2019

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第1阶段,MEDI1341的随机试验:大脑脊髓液中自由的α-synuclein降低了>50%

Craig Shering1, Michael Pomfret2, Robert J Kubiak3

  • 1Neuroscience, BioPharmaceuticals R&D, AstraZeneca, Boston, MA 02210, USA.

Brain communications
|September 12, 2025
PubMed
概括

针对α-synuclein的抗体MEDI1341在帕金森病患者中显示出良好的安全性和耐受性. 它有效地降低了脑脊液中的α-synuclein水平,支持了进一步的临床开发.

关键词:
在CSF的CSF中,帕金森病是帕金森氏症的一种疾病.药学动力学上的药理学.药物动力学 药物动力学在安全方面,安全是安全的.

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