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Updated: Jul 28, 2026

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波尔突变子宫内膜癌:地平线上的新视角?

Daniele Fanale1, Lidia Rita Corsini1, Paola Piraino1

  • 1Section of Medical Oncology, Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy.

Frontiers in oncology
|September 12, 2025
PubMed
概括

在子宫内膜癌 (EC) 中的POLE基因突变与更好的结果和免疫治疗反应有关. 对POLE变异的基因测试可以指导遗传性癌症风险的预防和监测策略.

关键词:
波兰 波兰 波兰这是一种POLE-超变的亚型.这是子宫内膜癌的癌症.外核酶域突变的突变生殖系/体质的POLE变体.微卫星的不稳定性预后 预后 预后

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...