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Updated: Jan 18, 2026

Drug-Induced Senescence in Liver Cells Promotes M2 Macrophage Polarization: Implications for Tyrosine Kinase Inhibitor-Associated Hepatotoxicity
09:32

Drug-Induced Senescence in Liver Cells Promotes M2 Macrophage Polarization: Implications for Tyrosine Kinase Inhibitor-Associated Hepatotoxicity

Published on: October 17, 2025

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索拉费尼布到雷戈拉费尼布序列诱导的动脉样硬化心血管疾病:一个新的病例报告

Changli Xu1, Xianghua Quan2, Qie Guo2

  • 1Department of Cardiovascular Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Frontiers in oncology
|September 12, 2025
PubMed
概括

对肝细胞癌的索拉费尼布和雷戈拉费尼布连续治疗导致在基线风险低的患者中发生严重的动脉样硬化心血管疾病 (ASCVD). 在氨酸激酶抑制剂治疗期间,持续的心血管监测至关重要.

关键词:
动脉样硬化心血管疾病与药物相关的毒性与药物相关的毒性肝细胞癌是肝细胞癌.雷戈拉芬尼布的使用情况索拉芬尼布 (Sorafenib) 是一个氨酸激酶抑制剂 氨酸激酶抑制剂

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