在疑似易生性肠综合征的年轻患者中进行全肠囊内镜检查:自控可行性研究
Robert Benamouzig1, Walaa El Arja1, Bakthiar Bejou1
1Gastroenterology & Digestive Oncology Department, Avicenne University Hospital, AP-HP, Sorbonne Paris Nord University, Bobigny, France.
泛肠囊与生物测试相结合,为在年轻成年人中诊断刺激性肠综合征 (IBS) 提供了可行的结肠镜替代方案. 这种非侵入性方法有效地排除了胃肠道疾病,而不会影响IBS诊断.
科学领域:
- 胃肠病学 胃肠病学
- 医学诊断 医学诊断 医学诊断
- 内镜检查是指内镜检查.
背景情况:
- 刺激性肠综合征 (IBS) 诊断依赖于临床标准,但结肠镜检查是常见的,以排除其他消化系统疾病.
- 全肠 PillCamTM 克罗恩氏病囊可提供小肠和结肠的非侵入性检查.
研究的目的:
- 评估一种使用泛肠囊和生物测试的策略,以排除在患有IBS症状的年轻成年人中胃肠道疾病的可能性.
- 评估这一策略作为传统结肠镜检查的替代方案.
主要方法:
- 一项涉及42名成年人 (18-50岁) 的研究显示,他们患有IBS的慢性腹部症状.
- 27名患者接受了常规的生物测试,便calprotectin,全肠囊内镜和胃肠内镜.
主要成果:
- 泛肠囊在15名患者中发现了21种病变,结肠镜检测在7名患者中发现了11种病变;所有病变在临床上都是无意义的.
- 上部内镜检查透露了一个胃和一个胃MALT淋巴瘤通过活检.
- 所有患者都更喜欢囊内镜,而不是传统的内镜手术.
结论:
- 泛肠囊策略,结合生物测试,可用于排除患有IBS症状的年轻成年人胃肠道疾病.
- 这种方法不会影响IBS的诊断,患者更喜欢这种方法.
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