相关实验视频
Updated: Jan 18, 2026

A Cell Culture Model for Producing High Titer Hepatitis E Virus Stocks
Published on: June 26, 2020
患有急性肝炎E感染的老年患者的肠道微生物群
Miaomiao Li1, Meng Shi1, Changyi Ji2
1Department of Clinical Laboratory, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, China.
肠道微生物群的变化,包括Firmicutes和Bacteroidetes的增加,与老年患者的急性肝炎E (AHE) 有关. 在AHE中,Bacteroides fragilis的丰富性预测了非自我愈合的结果.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 肠道失调与严重的肝脏疾病有关.
- 关于急性肝炎E (AHE) 的老年患者肠道微生物群变化的数据有限.
研究的目的:
- 为了描述AHE的老年患者的肠道微生物群.
- 评估肠道微生物群与AHE老年患者的临床结果之间的关联.
主要方法:
- 来自58名AHE老年患者和30名老年健康对照的便样本的16S rRNA基因测序.
- 生物信息分析包括α多样性和STAMP.
- 使用统计分析和ROC曲线评估 *Bacteroides fragilis* 的预测潜力.
主要成果:
- 在AHE-老年人和健康对照之间,微生物多样性没有显著差异.
- 在AHE老年患者中增加了*Firmicutes*,*Lactobacillales*和*Bacilli*的相对丰度.
- *Bacteroidetes*和*Bacteroides fragilis*在非自我愈合的AHE患者中更为丰富.
结论:
- *细菌菌体*的丰富性使AHE老年患者与对照患者有所区别.
- *Bacteroidetes*可以预测老年AHE患者的康复结果.
- 研究结果表明,对于老年人AHE管理的新策略.
相关概念视频
Bacterial Flora of the Large Intestine
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Gastritis-II: Pathophysiology
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

