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Updated: Jan 18, 2026

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使用TOYOPEARL MX-Trp-650M混合模式树脂在盐或pH梯度化下有效地去除抗体聚合物

Jinyi Zhang1, Penglong Zhang1, Yifeng Li1

  • 1Downstream Process Development, WuXi Biologics, Waigaoqiao Free Trade Zone, Shanghai 200131, China.

Journal of biological methods
|September 12, 2025
PubMed
概括

TOYOPEARL MX-Trp-650M树脂可以有效地去除抗体聚合物. 这种混合模式树脂在盐或pH化下实现了优异的清除,在抗体净化中表现优于Capto MMC ImpRes. 最佳条件因场景而异.

关键词:
聚合物 聚合物 聚合物抗体是对抗体的一种.卡普托 MMC ImpRes 公司在MX-Trp-650M中使用.混合模式树脂 混合模式树脂盐的梯度梯度是盐的梯度.在pH梯度的梯度下,

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