刺激手腕针点PC6以预防术后恶心和吐:一个网络元分析
Anna Lee1, Jack Zhenhe Zhang1, Jing Xie2,3
1Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, Hong Kong.
The Cochrane database of systematic reviews
|September 12, 2025
概括
将PC6针点刺激与抗药结合使用可以减少术后恶心和吐 (PONV) 以及救援抗药的需要. 虽然PC6针点刺激可以引起轻微的副作用,但关于其频率和严重性的证据是不确定的.
科学领域:
- 麻醉学和疼痛管理
- 补充和替代医学 补充和替代医学
- 基于证据的医学基于证据的医学.
背景情况:
- 手术后恶心和吐 (PONV) 是手术和麻醉后的常见并发症.
- 目前的抗药物在预防PONV方面只能提供部分有效性.
- 针点PC6刺激是一种替代方案,但其相对有效性尚不清楚.
研究的目的:
- 为了比较PC6针点刺激的疗效和安全性,有或没有抗emetics,与假冒或抗emetics预防PONV.
- 通过网络元分析 (NMAs) 确定用于PONV预防的最有效的技术.
- 更新PC6针点刺激和抗药物组合的现有证据.
主要方法:
- 进行了对多个数据库的系统搜索,搜索到2025年6月的随机对照试验 (RCT).
- 包括RCT比较PC6针点刺激 (侵入性或非侵入性),药物治疗或PONV预防的假干预.
- 进行频率网络元分析 (NMA) 来比较相对影响,并使用CINeMA和GRADE评估证据的确定性.
主要成果:
- 与假药相比,联合的侵入性PC6针点刺激和抗药可能会减少术后恶心 (PON) 和术后吐 (POV).
- 侵袭性和非侵袭性PC6针点刺激,以及单独的抗药,都可能减少PON和POV.
- 结合的非侵入性PC6针点刺激和抗药可能会减少救援抗药的需要;PC6刺激可能会导致轻微的,短暂的副作用.
结论:
- 侵袭性和非侵袭性PC6针点刺激与抗药物相结合,似乎可以有效地减少PON和POV.
- 这些组合也可能减少对救援抗药物的需求.
- 虽然PC6针点刺激可能会产生轻微的副作用,但关于其确定性的证据非常低.
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