随着时间的推移,心力衰竭表型的流行率的变化及其与患者预后的关联
Agnieszka Doryńska1, Anna Drohomirecka2, Roman Topór-Mądry3
1Department of Epidemiology, Cardiovascular Disease Prevention, and Health Promotion, National Institute of Cardiology, Warszawa, Poland
Polish archives of internal medicine
|September 12, 2025
概括
心力衰竭的患病率与保存的喷射分数 (HFpEF) 和轻微减少的喷射分数 (HFmrEF) 增加,而心力衰竭与减少的喷射分数 (HFrEF) 减少. 尽管老年患者和并发症的增加,但心力衰竭患者的整体存活率有所改善.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 心力衰竭 (HF) 的患病率和表型在全球范围内各不相同.
- 了解高频表型的时间变化及其对结果的影响至关重要.
研究的目的:
- 评估HF表型流行的时间趋势.
- 评估这些趋势与患者特征和预后之间的关联.
主要方法:
- 对2597名住院高温肺炎患者 (2014-2019年) 的回顾性分析.
- 根据HF表型进行分层:HFrEF,HFmrEF,HFpEF.
- 评估表型流行,临床特征和随着时间的推移生存率.
主要成果:
- HFrEF的流行率下降了27%,HFmrEF和HFpEF分别增加了53%和92%.
- 年龄较大,患有更多并发病 (高血压,心房动,糖尿病,癌症) 的女性患者比例增加.
- 总体而言,5年生存率从48.4%提高到60.2%,HFrEF的增长最大.
结论:
- 发生了向HFpEF和HFmrEF的转变,与人口老龄化和伴随疾病负担增加并行.
- 尽管人口结构和并发症发生了变化,但HF患者的整体存活率有所改善.
- 存活率的增长在心力衰竭与减少喷射分数组中最为明显.
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