尼泊尔的外周动脉疾病的流行:一个横截面研究
Danielle J Wilson1, Jaclyn A Gellings1, Colleen Flanagan1
1Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Vascular
|September 12, 2025
概括
在尼泊尔,周围动脉疾病 (PAD) 影响了超过45岁的成年人的7.4%,随着年龄的增长而增加. 这项研究强调了该国需要提高血管疾病意识和资源的需要.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
- 流行病学 流行病学
背景情况:
- 周围动脉疾病 (PAD) 是低收入和中等收入国家 (LMICs) 的主要心血管问题.
- 由于人口结构的变化和心血管疾病的增加,了解尼泊尔的PAD患病率至关重要.
- 这项研究涉及尼泊尔未知的PAD患病率.
研究的目的:
- 为了确定45岁及以上尼泊尔成年人中PAD的患病率.
- 为了利用脚-手臂指数 (ABI) 查来检测PAD.
- 为尼泊尔未来的医疗保健规划和血管健康计划建立基准数据.
主要方法:
- 这是一项从2022年10月到2023年3月在尼泊尔进行的横截面研究.
- 招募了639名年龄≥45岁且没有先前PAD诊断的参与者.
- 由ABI定义的PAD<0.9;不包括不可压缩的容器 (ABI>1.4).
主要成果:
- 整体PAD患病率为7.4% (95% CI 5.6%-9.7%),不包括不可压缩的ABI,达到8.7%.
- 随着年龄的增长,PAD患病率随着年龄的增长而增加,在75岁以上的个人中,患病率高达12.1%.
- PAD与较高的心脏病率 (15%对4%) 和音 (26%对10%) 有显著的关联.
结论:
- 这是尼泊尔首次对PAD进行系统评估,显示患病率与南亚邻国的患病率相当.
- 在尼泊尔人中,PAD与心脏病和听症状有关.
- 迫切需要加强血管疾病教育和资源,鉴于血管外科手术能力有限 (每3100万人有25名外科医生).
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