饮食得分的炎症潜力和子宫内膜癌的风险:一个案例对照研究
Elahe Etesami1,2, Ali Nikparast3,4, Jamal Rahmani1
1Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Nutrition and cancer
|September 12, 2025
概括
通过饮食炎症指数 (DII),饮食炎症评分 (ISD) 和饮食炎症评分 (DIS) 测量的高饮食炎症潜力与伊朗妇女子宫内膜癌 (EC) 风险增加有关.
科学领域:
- 在瘤学瘤学.
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 慢性炎症是子宫内膜癌发生的一个关键因素.
- 关于饮食炎症潜力和子宫内膜癌 (EC) 风险的现有研究缺乏一致性,特别是在非西方人群中.
研究的目的:
- 调查伊朗女性饮食炎症指数与EC风险之间的关联.
- 评估特定饮食模式在子宫内膜癌发展中的作用.
主要方法:
- 一项基于医院的病例控制研究,涉及136例EC病例和272例对照.
- 用经过验证的半定量食品频率调查问卷评估的饮食摄入量.
- 使用条件回归计算和分析了四种饮食炎症指数 (DII,EDIP,ISD,DIS).
主要成果:
- 与对照组相比,在EC病例中观察到显著更高的DII,ISD和DIS得分 (p < 0.001).
- 增加的DII,ISD和DIS与增加的EC风险有关 (ORs从2.45到3.37不等).
- 经验性饮食炎症模式 (EDIP) 在完全调整后没有显示出与EC风险的显著关联.
结论:
- 具有较高炎症潜力的饮食 (DII,ISD,DIS) 与伊朗妇女的子宫内膜癌风险增加有关.
- 针对炎症的饮食干预措施可能对EC预防策略至关重要.
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