在未破裂动脉瘤的支架辅助卷圈过程中,手术内肝素化的结果
Takashi Fujii1, Shuta Maehara1, Yoshimasa Fukui1
1Department of Neurosurgery, Fukuoka Neurosurgical Hospital, Fukuoka, Japan.
The neuroradiology journal
|September 12, 2025
概括
在支架辅助线圈栓塞期间的全身肝素化可能会减少未破裂的大脑动脉瘤治疗后的小缺血斑点. 然而,它可能会增加出血并发症和不良结果的风险.
科学领域:
- 神经外科 神经外科
- 干预性神经辐射学
- 血管神经学 血管神经学
背景情况:
- 未破裂的大脑动脉瘤需要有效的治疗来防止破裂.
- 支架辅助线圈栓塞是一种常见的内血管技术.
- 在这种手术中,手术内全身肝素化的作用尚不完全理解.
研究的目的:
- 为了比较使用支架辅助线圈栓塞治疗的未破裂动脉瘤的治疗结果,包括和没有全身肝素化.
- 为了评估手术内全身肝素化疗法的疗效.
主要方法:
- 一项对106名患者进行的比较研究,这些患者在未破裂的动脉瘤中接受了支架辅助的线圈栓塞.
- 患者被分为系统性肝化和非系统性肝化组.
- 术后第一天的头部MRI评估了缺血焦点;并发症和修改的兰金尺度 (mRS) 评分被评估.
主要成果:
- 非系统性肝素化组在MRI上显示了较多小缺血焦点的趋势 (P = .0583).
- 两组之间没有观察到缺血或出血并发症发生率的显著差异.
- 系统性肝素化组的患者比例较高,结果较差 (mRS 5-6).
结论:
- 术内全身性肝硬化可能会减少在支架辅助线圈栓塞后在术后第一天的MRI上扩散权重成像高信号斑点.
- 系统性肝化可能与较高的不良结果和出血并发症风险有关.
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