骨质疏松症的中期过渡率:老年亚洲人的DXA分析
Vu Pham Thao Vy1, Yi-Chien Lu2, James F Griffith3
1International Ph.D. Program in Medicine, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
Archives of osteoporosis
|September 12, 2025
概括
骨质疏松症的严重程度预测了老年人骨质疏松症的风险. 65岁以上患有严重骨质疏松症的女性需要密切监测,因为骨质疏松症的过渡率更高.
科学领域:
- 老年学是一门学科.
- 骨健康 骨健康 骨健康
- 骨质疏松症研究 骨质疏松症研究
背景情况:
- 骨质疏松症是人口老龄化中的一个重大健康问题.
- 双能X射线吸收计 (DXA) 对于评估骨矿物质密度 (BMD) 是至关重要的.
- 了解从骨质疏松症到骨质疏松症的过渡率对于风险分层至关重要.
研究的目的:
- 根据老年亚洲成年人的基线BMD来确定转移到骨质疏松症的速度.
- 为了评估50岁及以上个体的骨质疏松症的发展.
主要方法:
- 对1781名参与者 (1211名女性,570名男性) 进行了回顾性审查,并进行了重复的BMD测试.
- 根据T-得分分层分为正常的BMD,轻度,中度和严重的骨质疏松症组.
- 在<2年和2-5年的随访间隔中评估骨质疏松症的过渡率.
主要成果:
- 在32.62%的参与者中,整体过渡到骨质疏松症发生.
- 过渡率在女性 (23.5%) 显著高于男性 (11.1%).
- 骨质疏松症的发病率随骨质疏松症的严重程度而增加,在2-5年内患有严重骨质疏松症的妇女中达到45.9%.
结论:
- 骨质疏松症的严重程度与骨质疏松症风险的增加密切相关,特别是在老年妇女中.
- 建议对65岁以上患有严重骨质疏松症的妇女进行密切监测.
- 针对骨质疏松症的有针对性的重新查应优先考虑患有中度至重度骨质疏松症的老年人.
更多相关视频
09:02Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
Published on: January 31, 2025
1.5K
07:12Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
Published on: September 28, 2017
8.6K
相关概念视频
01:29Bone Disorders
5.1K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.1K
01:31Osteoclasts in Bone Remodeling
3.9K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.9K
01:40Bone Remodeling
40.3K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.3K