使用生存分析方法对五岁以下儿童死亡率和相关风险因素的生存分析
Abdul-Karim Iddrisu1, Emmanuel Boanyo2
1Department of Statistics, School of Social Sciences, Faculty of Social Sciences, University of Botswana, Gaborone, Botswana.
PLOS global public health
|September 12, 2025
概括
这里是加拿大加拿大加拿大加拿大.
科学领域:
- 儿童健康 儿童健康
- 人口统计学 人口统计学
- 公共卫生 公共卫生
背景情况:
- 五岁以下儿童死亡率是医疗保健系统绩效和实现可持续发展目标 (SDG) 3.2的进展的一个关键指标.
- 加纳已经减少了儿童死亡率,但儿童死亡率仍高于SDG 3.2的目标,即每1000个活产婴儿死亡25例.
- 确定五岁以下儿童死亡率的预测因素对于有针对性的干预和基于证据的政策制定至关重要.
研究的目的:
- 用先进的生存建模技术,确定加纳五岁以下儿童死亡率的关键预测因素.
- 通过使用扩展的Cox-PH和贝叶斯多层次生存分析来解决传统模型的局限性.
- 为加纳加快实现可持续发展目标3.2的进展提供见解.
主要方法:
- 利用了2022年加纳人口与健康调查 (GDHS) 的数据.
- 员工扩展了Cox比例危险 (Cox-PH) 模型,以考虑随时间变化的共变量效应.
- 应用贝叶斯生存分析和多层次建模,以获得稳定的估计和处理未观察到的异质性.
主要成果:
- 男性性别,双胞胎出生,剖腹产和更大的出生尺寸与增加五岁以下儿童死亡风险有关.
- 按期分娩,更高的母亲教育和更大的家庭财富显示出保护作用.
- 在分娩后需要特别注意的儿童的生存率有所改善.
结论:
- 社会经济因素,如母亲的教育和家庭财富显著影响儿童生存率.
- 有针对性的干预措施应侧重于加强孕产妇和新生儿护理,减少社会经济差距.
- 解决已识别的风险因素对于加纳实现其可持续发展目标3.2关于儿童死亡率的目标至关重要.
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