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Updated: Jan 18, 2026

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无线启动和读取无标签纳米传感器,用于实体监测活体动物蛋白质度

Hassan Raji¹, Suneel Kumar², Zhuolun Meng¹

¹Department of Electrical and Computer Engineering, Rutgers University, Piscataway, New Jersey 08854, United States.

Langmuir : the ACS journal of surfaces and colloids

|September 12, 2025

概括

这项研究引入了一种新的无线生物传感器,用于实时跟踪活体动物的炎症. 非侵入式传感器准确量化蛋白质生物标志物,改善伤口护理和患者的治疗结果.

科学领域:

生物医学工程生物医学工程
生物传感器技术技术
在实体监控中进行实体监控.

背景情况:

炎症生物标志物的实时跟踪对于有效的临床干预至关重要.
有线传感器存在局限性,包括限制移动,感染风险和持续监控的不便.

研究的目的:

开发和验证一种新的无线,无标签的电子生物传感器,用于实时量化活动物中的蛋白质生物标志物.
克服传统有线传感器在体内炎症监测的局限性.

主要方法:

一个无线生物传感器,利用共振感应合进行功率传输和远程阻抗测量.
在3D打印结构中整合一个接收器电路,用于伤口应用.
通过IL-6定位和体内测试对30只带有诱导伤口的动物进行实验验证.

主要成果:

无线生物传感器成功实现了对活动物中的蛋白质生物标记物的无标签实时量化.
测量结果显示与标准ELISA结果有很强的相关性 (R2>0.9).
3D打印的接收器电路被优化为在伤口上有效应用.

结论:

开发的平台提供了一种非侵入性,实时和便携式的方法来跟踪炎症.
这项技术有可能显著改善伤口护理管理和患者的治疗结果.
这代表了无线生物传感在体内应用中的新进展.

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