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Updated: Jul 15, 2026

Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy
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从iPSC衍生的心肌细胞设计功能性心脏组织的进展:建筑和应用方面的进展

Meiyi Huang1, Sitian Liu1, Xiong Zhou1

  • 1Guangdong Provincial Key Laboratory of Digital Medicine and Biomechanics, Department of Human Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.

Acta biomaterialia
|September 12, 2025
PubMed
概括

使用人类诱导的多能干细胞衍生的心肌细胞 (iPSC-CMs) 的工程心脏组织提供先进的疾病建模和再生疗法. 本综述详细介绍了iPSC-CM的差异化,组织工程方法以及未来的临床应用.

关键词:
心脏肌细胞是心脏肌细胞.工程心脏组织的工程心脏组织.心脏在芯片上的心脏人类诱导的多能干细胞干细胞.心肌修复是心肌的修复.

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相关概念视频

iPS Cell Differentiation01:22

iPS Cell Differentiation

The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.