在安慰剂和重新评估机制中明显的前额叶侧面化:ALE元分析
Bianca Monachesi1, Elisabetta Pisanu1, Daniele Chiffi2
1Neuroscience Area, SISSA, Trieste, Italy.
NeuroImage
|September 12, 2025
概括
认知重新评估和安慰剂效应共享大脑区域,如背侧前额皮层 (DLPFC),用于情绪调节. 然而,重新评估主要使用左边的DLPFC,而安慰剂效应则使用右边的DLPFC,表明了不同的神经机制.
科学领域:
- 神经科学是一个神经科学.
- 认知心理学 认知心理学
- 精神病学是一个精神病学.
背景情况:
- 认知重新评估是一种情绪调节策略,涉及改变视角.
- 安慰剂效应涉及主观和生理反应的信念驱动调节.
- 两者可能共享神经支,但缺乏直接比较.
研究的目的:
- 系统地比较认知重新评估和安慰剂效应的神经网络.
- 通过全脑元分析方法来研究共享和独特的大脑区域.
主要方法:
- 基于坐标的激活概率估计 (ALE) 的元分析.
- 包括基于任务的功能磁共振成像 (fMRI) 研究.
主要成果:
- 重新评估和安慰剂效应都会影响背侧前额皮层 (DLPFC).
- 重新评估主要激活左侧DLPFC,腹侧PFC和背中PFC.
- 安慰剂效应主要激活了右侧的DLPFC.
结论:
- 共享的认知控制机制存在,但重新评估和安慰剂效应在神经生物学上有所不同.
- 在DLPFC内部的侧面化表明了不同的神经通路.
- 这些发现对在临床环境中理解情绪调节和安慰剂反应有影响.
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