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产前胎儿大脑的扩散核磁共振:一个方法学范围审查

M Di Stefano¹, T Ciceri², A Leemans³

¹NeuroImaging Laboratory, Scientific Institute IRCCS Eugenio Medea, Bosisio Parini, Italy; Image Sciences Institute, Division Imaging and Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.

|September 12, 2025

概括

胎儿扩散权重磁共振成像 (dMRI) 显示出评估胎儿大脑发育的前景. 由于异质性,需要对方法进行标准化,但人工智能方法正在出现.

科学领域:

神经成像是一种神经成像.
发育神经科学的发展神经科学.
医疗成像医学成像

背景情况:

胎儿扩散权重磁共振成像 (dMRI) 是研究胎儿大脑发育和白质组织的关键工具.
尽管研究增加,胎儿dMRI方法的标准化在临床和研究环境中缺乏.

研究的目的:

进行范围审查,合成胎儿dMRI大脑数据分析的方法方法.
确定胎儿dMRI研究中的当前应用和新兴趋势.

主要方法:

对54篇关于胎儿dMRI的相关文章进行了系统审查.
分析重点是数据集,采集协议,预处理,图像处理/建模和大脑地图结构.

主要成果:

扩散张力成像 (DTI) 和确定性曲谱法通常用于分析纤维特性和组织.
观察到越来越多的先进技术趋势,包括基于人工智能的方法,以克服胎儿的dMRI限制.
方法的异质性和缺乏公共数据/工具,阻碍了胎儿大脑dMRI的充分潜力.

结论:

胎儿dMRI对研究健康和病理条件下的大脑发育具有临床价值.
解决方法异质性和促进数据共享对于推进该领域至关重要.
新兴的人工智能技术显示出改善胎儿dMRI分析的希望.

关键词:

大脑发育大脑发育扩散张力成像扩散张力成像胎儿的dMRI是什么曲谱学曲谱学曲谱学曲谱学

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