呼吁及时预防甲状腺眼病:从IRTED注册表中吸取教训
Nasser Karimi1, Shadi Akbarian1, Hossein Ghahvehchian1
1Eye Research Center, Department of Ophthalmology, The Five Senses Health Institute, Moheb Kowsar Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran (the Islamic Republic of).
The British journal of ophthalmology
|September 12, 2025
概括
确定推迟甲状腺眼病 (TED) 诊断的危险因素至关重要. 男人和老年人面临更高的风险,需要针对性干预以获得更好的结果.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 甲状腺眼病 (TED) 诊断和治疗延迟是重大的临床挑战.
- 了解导致TED识别延迟的因素对于改善患者护理至关重要.
研究的目的:
- 确定与甲状腺眼病 (TED) 延迟诊断和治疗相关的因素.
- 为提前识别和管理TED患者提供建议.
主要方法:
- 来自伊朗TED (IrTED) 登记册数据的回顾性分析 (2013年3月-2023年).
- 对685名TED患者的人口统计,临床活动/严重性指数和与延迟呈现相关的因素的检查.
- 使用了欧洲坟墓轨道病学小组的分类标准.
主要成果:
- 诊断时的平均年龄为37.79岁;37.66%的人有甲状腺功能障碍的第一级家族病史.
- 56.49%的人有中度至重度的TED,5.40%的人有视力威胁的TED.
- 男人有5倍可能有活跃的TED,有10倍可能有视力威胁的TED. 年龄的增加与较高的活跃和视力威胁TED的几率相关.
结论:
- 主要预防:识别甲状腺功能障碍病例的亲属可以最大限度地减少TED的进展.
- 二次预防:男性和老年患者需要更早的诊断,以防止严重的表现.
- 三级预防:临床活动得分值为3错过了34.91%的活跃TED病例,表明需要修订评估.
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