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Updated: Jan 18, 2026

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绘制阿拉比多氨基转移酶的多基质特异性

Kaan Koper1, Marcos V V de Oliveira1, Sebastian Huß2,3

  • 1Department of Botany, University of Wisconsin-Madison, Madison, WI, USA.

Nature plants
|September 12, 2025
PubMed
概括

研究人员通过表征38种阿拉比多普西斯氨基转移酶来探索植物代谢. 他们的发现揭示了酶乱交增强了代谢网络,对于提高作物中使用效率至关重要.

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Allosteric Proteins-ATCase

Binding sites linkages can regulate a protein's function.  For example, enzyme activity is often regulated through a feedback mechanism where the end product of the biochemical process serves as an inhibitor.
Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to  N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis...
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