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Updated: Jan 18, 2026

Experimental Approaches to Study Mitochondrial Localization and Function of a Nuclear Cell Cycle Kinase, Cdk1
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Published on: February 25, 2016

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通过CDK1-介导的LDHA酸化,通过依赖LDHB的乳酸氧化,促进了Mitosis

Mengting Liu1, Aoxing Cheng1, Weiyi You2

  • 1Department of Digestive disease, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230027, China.

EMBO reports
|September 12, 2025
PubMed
概括

乳酸脱酶B (LDHB) 对于癌细胞线粒分裂至关重要,而不是LDHA. 通过CDK1介导的LDHA酸化将LDH活动转移到产生NADH,在转化过程中推动癌细胞的能量产生.

关键词:
这就是ATPATPATP ATP.乳酸盐是一种乳酸盐.乳酸脱酶的使用方法线粒分裂 (mitosis) 是一种发生在细胞的过程.它们是NADH和NADH.

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