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Updated: Jan 18, 2026

DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling
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对特定序列的DNA结合蛋白的计算设计

Cameron J Glasscock1,2,3, Robert J Pecoraro4,5,6, Ryan McHugh4,5

  • 1Department of Biochemistry, University of Washington, Seattle, WA, USA. cjamesglasscock@gmail.com.

Nature structural & molecular biology
|September 12, 2025
PubMed
概括

研究人员开发了一种计算方法来设计新的DNA结合蛋白 (DBPs). 这些工程 DBP 识别特定的 DNA 序列,并在细胞中起作用,用于基因调节和编辑应用.

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