结合蛋白质,益生菌和运动疗法治疗萨尔科佩尼亚:全面的审查
Ryuk Jun Kwon1,2,3, Mohammad Al Mijan1, Soo Min Son1,2,3
1Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.
Cells
|September 13, 2025
概括
这篇评论探讨了将食蛋白,益生菌和运动结合起来,以对抗肉类症. 这些干预措施可以协同增强老年人肌肉健康和功能.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 运动生理学 运动生理学
背景情况:
- 随着年龄的增长,肌肉质量和力量的丧失,即萨尔科佩尼亚,构成了全球重大的健康挑战.
- 目前对肉类的治疗方法有限,越来越关注生活方式干预.
- 饮食中的蛋白质,益生菌和炼被认为是治疗萨科佩尼亚的关键策略.
研究的目的:
- 审查将饮食蛋白质,益生菌补充剂和多式运动结合起来,用于治疗肉症的潜力.
- 探索由这些干预影响的互补效应和共享的细胞内通路.
- 突出一种多式模式的方法来增强肉类的个体的肌肉健康.
主要方法:
- 审查关于蛋白质,益生菌和运动在sarcopenia的临床前和机械学研究.
- 分析证据支持每个干预措施单独和组合的有效性.
- 研究共享的分子通路,包括mTOR信号传递,FOXO3a抑制和线粒体生物发生.
主要成果:
- 饮食中的蛋白质支持肌肉蛋白质的合成,并防止肉症的肌肉损失.
- 益生菌显示出肌肉再生,增加蛋白质合成和改善运动表现的新兴证据.
- 多式运动有效地增强了肌肉力量,运动能力和身体功能在sarcopenic个体.
结论:
- 结合饮食中的蛋白质,益生菌和多式运动提供了一种有前途的,补充的策略,用于萨科佩尼亚管理.
- 这些干预措施可以通过激活共享的细胞内通路来协同工作,以支持肌肉健康.
- 采用多式模式的方法有可能提高老年人患有肉类的生活质量.
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