在转移性结直肠癌中使用抗EGFR疗法:识别,跟踪和克服抗性

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Updated: Jan 18, 2026

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure
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Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

Published on: August 11, 2017

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Luís Felipe Leite1, Mariana Macambira Noronha2, Junior Samuel Alonso de Menezes3

  • 1Department of Medical Sciences, Universidade Federal Fluminense, Niteroi 24220-140, RJ, Brazil.

Cancers
|September 13, 2025
PubMed
概括

负的超选择提炼了患者选择表皮生长因子受体 (EGFR) 抑制剂在转移性结直肠癌 (mCRC). 综合性分析可以确定耐药性机制,改善治疗结果并指导未来的治疗方法.

关键词:
抑制了EGFR的发生.在循环中的瘤DNA.转移性结直肠癌 转移性结直肠癌消极的超选择是负的.精确瘤学 精确瘤学

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