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Updated: Jan 18, 2026

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在口腔状细胞癌中,PIAS1通过抑制免疫逃避来形成抑制瘤的微环境

Parisa Ghahremanifard1,2, Jinsu An1,2, Ayan Chanda1,2

  • 1Department of Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB T2N 4N1, Canada.

Cancers
|September 13, 2025
PubMed
概括

在口腔癌中,激活STAT1 (PIAS1) 的蛋白抑制剂促进了抗瘤免疫力. 瘤细胞和免疫细胞中的PIAS1表达重新编程了瘤微环境,表明PIAS1是治疗点.

关键词:
在 PIAS1 的基础上.口腔状细胞癌的癌症.一个单细胞RNA-seqq.瘤微环境是一个微环境.

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