炎症性肠病中的生活质量和疲劳:系统性审查
Maheeba Abdulla1, Nafeesa Mohammed2, Jehad AlQamish1
1Department of Internal Medicine, Ibn Al Nafees Hospital, Road 3302, Manama P.O. Box 54533, Bahrain.
Healthcare (Basel, Switzerland)
|September 13, 2025
概括
与健康人相比,患有炎症性肠病 (IBD) 的患者的生活质量显著降低,疲劳增加. 需要进一步的研究来了解IBD在全球的长期影响.
科学领域:
- 胃肠病学 胃肠病学
- 临床医学 临床医学
- 患者的治疗结果.
背景情况:
- 炎症性肠病 (IBD) 包括诸如克罗恩病和性结肠炎等慢性疾病.
- IBD显著影响患者的日常生活,影响身体和精神健康.
- 关于IBD患者与健康对照患者的生活质量和疲劳的比较数据有限.
研究的目的:
- 系统地评估和比较成人IBD患者与健康对照者的生活质量和疲劳水平.
- 综合当前关于患者报告的炎症性肠病结果的证据.
主要方法:
- 在Medline和Embase数据库 (2015年1月 - 2025年4月) 中进行了全面的文献搜索.
- 包括的研究集中在没有并发症的IBD成年患者身上,与健康对照人群相比,并测量了生活质量和疲劳.
- 研究选择,数据提取和质量评估由两位评论员独立进行;由于异质性,结果被叙述性合成.
主要成果:
- 分析了10项涉及10661名参与者的研究.
- 三项研究表明,IBD患者的精神和身体生活质量成分显著下降.
- 三项研究报告说,与对照人群相比,IBD患者的疲劳患病率更高.
结论:
- 与健康人群相比,患有炎症性肠病 (IBD) 的成年患者表现出明显降低的生活质量和更高的疲劳患病率.
- 建议进行长期后续研究,以阐明IBD的全面全球影响,特别是在代表不足的非西方人群中.
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